ENHANCEMENT OF PYOCYANIN PRODUCTION BY SUBINHIBITORY CONCENTRATION OF ROYAL JELLY IN PSEUDOMONAS AERUGINOSA [VERSION 3; PEER REVIEW: 2 APPROVED, 1 APPROVED WITH RESERVATIONS]

Background: Pseudomonas aeruginosa, a multidrug-resistant Gram-negative bacterium, produces pyocyanin, a virulence factor associated with antibiotic tolerance.High concentrations of royal jelly have an antibacterial effect, 5326058hx which may potentially overcome antibacterial resistance.However, in some cases, antibiotic tolerance can occur due t

Abstract Breakwaters are essential constructions providing tranquility to ports and harbour structures, when read more there is a lack of natural protection measures.Traditionally these massive structures are constructed using natural rocks weighing tonnes.In the present scenario, obtaining huge natural rocks are difficult as well as non-eco-friend

This commentary offers an analysis of the Treaty on the Prohibition of Nuclear Weapons (TPNW), its strengths, weaknesses, relationship to other agreements as well as recent updates.Indicating the urgency in enacting nuclear disarmament, nuclear threats loom over two of the major conflicts we are facing today: here the danger of nuclear proliferatio

Summary: Analysis of The Cancer Genome Atlas and other published data of head and neck squamous cell carcinoma (HNSCC) reveals somatic alterations of the Hippo-YAP pathway in approximately 50% of HNSCC.Better strategies to target the YAP1 transcriptional complex are sought.Here, we show that FAT1, an upstream inhibitor of YAP1, is mutated either by